Co-Olesta Tab is a combination drug especially developed for the treatment of hypertension, often known as high blood pressure, a common disease that can result in a number of health issues. This drug combines two powerful active components, olmesartan medoxomil and hydrochlorothiazide, which operate in tandem to lower and manage blood pressure. The angiotensin II receptor blocker, olmesartan medoxomil prevents angiotensin II from binding to receptors in the body. This procedure prevents blood vessel constriction, which lowers blood pressure. Olmesartan medoxomil reduces blood pressure and prevents hypertension-related problems by inhibiting this key chemical messenger. The medicine should be used as prescribed by the doctor.